Supplement Reviews

10 Best Joint Supplements to Relieve Pain

Joint Pain Relief
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If you’ve ever woken up with a stiff neck or need to warm up your knees before standing, it may indicate that you have a joint condition.

It might be that you’re struggling to go about your daily life activities without pain or even be hobbies that you no longer enjoy as your joints are too painful. If that sounds familiar, you could benefit from help in the form of a joint supplement.

In America, as many as 23% of all adults have arthritis (over 54 million people), and around half of them find their daily activities limited by their condition. But arthritis isn’t the only joint condition that causes pain. When you add in the number of people suffering from joint injuries, as well as osteoporosis and fibromyalgia, the numbers continue to grow.

Joint supplements are a safe, natural, and effective way to get relief from joint pain and, depending on the nature of your joint condition, can offer lasting benefits.

What causes joint pain?

Arthritis is the most common cause of joint pain, and the two main types are osteoarthritis and rheumatoid arthritis.

Osteoarthritis is the most common form in adults over the age of forty, typically affecting the hips, knees, hands, and wrists. The condition develops over time when your cartilage, the protective cushion in between the bones, wears away, causing the joints to become painful and stiff.

Rheumatoid arthritis, the other form of arthritis, affects as many as 1.5 million Americans (mostly women) and leads to joint deformity over time. This form of arthritis causes pain, inflammation, and a fluid build-up as the body’s immune system starts to attack the joint linings.

Other common causes of joint pain include bursitis (inflammation of the pads that cushion the joints), lupus, gout, tendinitis, joint injuries and overuse, osteoporosis, and fibromyalgia.

How to choose the best joint supplement

If you suffer from joint pain, there’s a good chance that you’ve considered taking vitamins and supplements for pain relief as well as to address symptoms such as loss of flexibility and a reduced range of motion.

Best Joint Supplements

But choosing a supplement to help with joint pain is overwhelming for many people due to the sheer number of options that contain different ingredients, all claiming to offer the results you need. When it comes to supplements, more doesn’t necessarily mean better. A long list of ingredients doesn’t always mean that you’ll get better results, and there might easily be ingredients that don’t offer any benefits for joint health.

You have to consider the inconsistency of labels and the absence of regulations in the natural products industry. Joint supplement manufacturers do not have to adhere to strict regulations around the research they conduct, the marketing that they do, and quality assurances that they offer. This makes it vital to make an informed decision based on your research when selecting a supplement. The two most important areas to consider when choosing a supplement are the ingredients and the quality of the product.

Joint Supplement Ingredients

There are several important compounds that can help with joint conditions, such as:


Glucosamine is linked to the stimulation of the immune system, relieving joint stress (especially after strenuous exercise) and supports the development of healthy cartilage. Other additional benefits include increased range of motion for joints, improved mobility, and overall joint health. As we age, Glucosamine levels decline, making supplementation important for older men and women.


Chondroitin occurs naturally in the body and is known to stimulate healthy cartilage and support tissue recovery after exercise or injury. It can help reduce joint aches and pain and also supports collagen health.

MSM (Methylsulfonylmethane)

This is a bioavailable compound that is linked to supporting the development of healthy tissue and improved range of motion in the joints and may also play a role in improved immune function.


Turmeric is a significant anti-inflammatory proven to help with joint pain, stiffness, and inflammation. It contains bioactive compounds that inhibit joint degradation as well as supporting overall health.


This centuries-old frankincense originates in India and has been used for hundreds of years to treat arthritis naturally.


Hydrolyzed collagen can support elasticity in the connective tissue as well as promoting strong, healthy bones.

Hyaluronic Acid

Hyaluronic Acid occurs naturally in the body and helps to cushion and lubricate the joints.

Vitamin D

Vitamin D is essential for the optimal functioning of your muscles, bones, and immune system.

Joint Supplement Quality

To choose the best joint supplement, there are several factors to consider, including:

  • Potency per serving, the number and concentration of active ingredients (such as Glucosamine and Chondroitin) can vary widely, so you need to choose a supplement that offers the best potency per serving. This may take a bit of calculation as the number of capsules per serving can vary, and the type of Glucosamine may be different (such as Glucosamine HCl, which has higher levels of Glucosamine compared with Glucosamine Sulfate).
  • Herbs with anti-inflammatory properties, these include turmeric curcumin and Boswellia extract that, have research showing their ability to reduce and control inflammation.
  • Natural ingredients, if you are choosing a joint supplement, it should be completely natural. This means that it should be free from heavy metals as well as soy, dairy, magnesium stearate, and silicon dioxide.
  • Faster, effective absorption, where possible, verify the bioavailability of the supplement to ensure that you’re getting the right dosages in a format that your body can use. Then check that there are no binders or fillers that will slow the product’s release and absorption.
  • Scientific formulation, the supplement should be backed by years of clinical research and testing to ensure that the product is both safe and effective.
  • Label transparency, it is important to choose a supplement that discloses the dosages of individual ingredients on the label.
  • A reputable brand, check that the manufacturer has a strong reputation and a long track record of supplying safe, effective natural health products.
  • Third-party testing, in an industry that is known for inaccurate labeling, independent third-party offer the user peace of mind that the product is safe to consume, is pure (free from heavy metals and other contaminants), and has the advertised level of potency.
  • GMP-Certification, this ensures that the supplements have been produced in accordance with Good Manufacturing Practice.
  • Made in the USA, products made within the US are more likely to adhere to strict quality control processes and methodologies and should be submitting each new batch for independent testing.

Now that you have a better idea of what you’re looking for, we can take a look at the top joint supplement brands on the market.

Vimerson Health Glucosamine with Chondroitin, Turmeric & MSM

Vimerson Health Joint Supplement

Vimerson’s industry-leading joint supplement for men, women, and seniors has over 5000 reviews and consistently achieves high ratings across the board. The supplement offers relief from joint pain, helps control your body’s inflammatory response, and has antioxidant properties. Each bottle contains 90 capsules, and they can be taken for your back, knees, and hands to ease joint discomfort that comes with weight, age, or athletic deterioration.

Research into the benefits of Vimerson’s Health Glucosamine indicates that it may help with joint lubrication to improve joint functionality. It promotes joint health and comfort while supporting cartilage and joint flexibility.

The unique blend includes Glucosamine, Chondroitin, Turmeric, MSM, Boswellia, Quercetin, Methionine, and Bromelain, all compounds that are linked to improving joint health, as well as the joint’s range of motion and relief from pain.

Vimerson’s commitment to quality means that they follow strict quality control standards from formulation to manufacturing, allowing them to offer the highest-quality supplements. This USA-made Glucosamine can be taken by vegetarians and is free from hormones, dairy, soy, yeast, gluten, sugar, cholesterol, artificial colors and flavors, and binders.

Arazo Nutrition Joint Support

Arazo Joint Supplement

With thousands of five-star reviews, this affordable supplement is ideal for joint support and joint pain relief. Each bottle contains 180 capsules, packed with 1500mg of Glucosamine, 1200mg of Chondroitin, and 1000mg of MSM.

The main joint health benefits offered by this supplement are improved joint mobility, easing of stiff joints, the repair of damaged cartilage, improved protection, and cushioning for joints. The supplement has been scientifically formulated based on available research to contain a powerful blend of Glucosamine, Chondroitin, MSM and Hyaluronic Acid, Turmeric, and Boswellia that together reduce pain, aches, and inflammation in the joints.

The supplement has been crafted to restore lubrication and collagen in the joints as well as building joint strength for men, women, and seniors. As a result, users enjoy improved mobility and flexibility in their joints as well as an increased sense of overall well-being.

Azaro’s formula is made in the USA in an FDA and GMP-certified facility, and all products are tested by an independent third party for purity. They are designed to offer a complete dietary supplement for joints that repairs cartilage, increases joint flexibility and mobility, supports the joint’s structure, and protects the delicate joint tissue. The Hyaluronic Acid added to the formula acts as a lubricating agent and as a shock absorber for vulnerable joints.

Many customers choose Azaro over other joint support supplements because it offers relief for aching joints and helps with the reduction of swelling. It’s also affordable and convenient, making it a supplement that customers continue to repurchase.

Zenwise Glucosamine Chondroitin Sulfate MSM Curcumin

Zenwise Joint Supplement

Zenwise delivers extra strength joint support with this highly-rated, popular advanced joint supplement. Combining a unique blend of ingredients, the supplement is used by men and women with joint-related pain and discomfort. Zenwise’s supplement formulation contains Glucosamine and Chondroitin for healthy cartilage and tissue and is supported by MSM for healthy collagen. The complex also contains Curcumin that is linked to joint flexibility as well as Hyaluronic Acid for joint mobility and comfort. Zenwise Health Joint Support contains 1500mg Glucosamine, 1200mg Chondroitin, and 1000mg MSM.

Zenwise is a well-established natural health company that supports a healthy and active lifestyle. For this reason, they design safe, effective solutions to common conditions that can have a severe negative effect on your quality of life. The primary benefits of this supplement include healthy tissues and cartilage from Glucosamine and Chondroitin, improved joint mobility from Hyaluronic Acid, better joint strength from MSM, and better flexibility and range of motion from Curcumin.

As the nutritional science advances forward with new breakthroughs, Zenwise Health is committed to supporting your healthy and active lifestyle by bringing you these exciting solutions in safe and highly effective products that you can trust.

Move Free Advanced Plus MSM

Schiff Move Free Joint Supplement

This highly rated, affordable product continues to be the joint supplement of choice for thousands of Americans. It effectively supports the five most important indicators of joint health which are mobility, flexibility, strength, lubrication, and comfort. Results from this supplement can offer improved joint comfort within two weeks.

The pills have been designed to be easier to swallow as coated pills that are smaller in size than others on the market. They contain Glucosamine and Chondroitin as the key ingredients necessary for the formation of cartilage as well as helping improve joint flexibility and cushioning. Glucosamine is an essential building block for healthy joints, while Chondroitin resists compression in the joints by attracting fluid for cushioning and lubrication. MSM (a source of sulfur that occurs naturally in the body) is added to support the formulation of collagen as well as supporting cartilage structure. Hyaluronic Acid offers improved joint lubrication, mimicking Hyaluronic Acid which is found in healthy joint fluid, necessary for joint lubrication and smooth joint function.

As an added benefit, Move Free has a great loyalty program that awards points based on your purchases and can be redeemed for rewards. And, as part of their commitment to offering Americans relief from joint pain, they are proud sponsors of the Arthritis Foundation, as well as research, advocacy, and education for those living with joint pain.

Schiff Glucosamine with Vitamin D3 & Hyaluronic Acid

Schiff Joint Supplement Vitamin D

If you’re looking for a supplement that’s going to help with the structure and function of the cartilage in your joints, Schiff’s Glucosamine, with its added vitamin D3 and Hyaluronic Acid might be the solution you’re looking for. The Hyaluronic Acid supports the works of the Glucosamine by adding lubrication to the joints for smooth movement, and vitamin D3 helps your body to maintain the correct levels of Calcium and Magnesium needed for strong bones.

It’s convenient as well as effective, and it is taken as a once-daily supplement. Because it’s once daily, it’s easier to remember to take and contains 2000mg of high potency Glucosamine HCl per serving along with Hyaluronic Acid, which occurs naturally within the body, particularly in healthy joint fluid. The tablets are also quick-acting as they use Sure Dissolve technology, which is designed to disintegrate within an hour to improve uptake and reduce waste.

The supplement’s high levels of active Glucosamine and high-quality formulation give users peace of mind that they are purchasing a top-of-the-range supplement with guaranteed freshness, purity, and the potency listed on the label. If you are taking joint supplements to manage joint pain related to aging, the Vitamin D in Schiff’s supplements can make a big difference. Vitamin D means that your bones are better able to absorb and retain calcium, which contributes to overall bone health and joint movement.

Compared to other brands, Schiff’s joint supplement contains higher levels of active Glucosamine (contained in Glucosamine Hydrochloride), whereas most have around 65% Glucosamine (as they use Glucosamine Sulfate).

As part of the Schiff Quality Guarantee, these joint supplements are completely pure, fresh and contain the potency advertised on the label; they are also free from preservatives and artificial flavors. Schiff is a trusted manufacturer of supplements, having been in the industry for over 70 years and their commitment to research and innovation makes them an industry leader.

BioSchwartz Glucosamine Chondroitin MSM Turmeric for Hip, Joint & Back Pain Relief

Bioschwartz Joint Formula Supplement

BioSchwartz’s anti-inflammatory supplement is ideal for joint pain relief. It contains Hyaluronic Acid, Collagen, Boswellia, Bromelain, and Fruitex-B. The all-natural supplement from BioSchwartz Glucosamine can be used to help build cartilage, increase joint flexibility and joint mobility, strengthen joint structure, protection joint tissue, and control inflammation. Whether your joint pain is related to age, weight, or sporting injuries, the capsule can reduce pain and ease discomfort.

This highly-rated supplement offers superior bioavailability, which makes it more easily absorbed by the body. This is thanks to the scientifically-backed addition of Fruitex-B. This 100% natural product is certified gluten-free, filler-free, binder-free, and non-GMO, as well as being free from gluten, soy, milk, dairy, wheat, nut, eggs, and corn.

It’s manufactured in the USA with professional-grade ingredients to produce a supplement that’s GMP-certified, and each batch is third-party tested. Part of the testing includes checking for heavy metals, solvent residues, pesticides, and toxins. Also, the supplement is formulated by doctors, so users have peace of mind that the supplements are of the best purity, potency, and quality.

The supplement is ideal if you suffer from joint discomfort in your hands, wrists, back, neck, elbows, knees, hips, or ankles. It is a multi-faceted supplement for both men and women, designed specifically for those who experience joint pain, stiffness or stress, addressing the root of the problem and offering increased flexibility, support, and protection for joints.

It is more effective than many other brands as it combines the perfect balance of potent ingredients for the best levels of efficacy and offers quick results. Glucosamine, Chondroitin, and MSM improve joint health and help to reduce pain, and are complemented by other components that offer complete joint support. This includes the patented Fruitex-B, Boswellia Extract, and Turmeric Curcumin.

Team 6 Cryotherapy – Natural Joint Support Supplement

T6 Cryotherapy Joint Supplement

For joint pain relief that works, T6’s Cryotherapy continues to be one of the top-rated, best-performing supplements on the market. Using a clinically proven combination of trademarked ingredients, Team Six has swapped out the more widely-used Glucosamine and Chondroitin ingredients to create an all-natural, powerfully effective product.

This brand and formula is widely popular in the body-building community. Also, it’s important to note there are many natural ways you can protect your joints.

Designed to support complete cartilage and bone health, the supplement includes trademarked fruiteX-B calcium fructoborate and UC-II Type II collagen. Both are proven to offer effective pain relief for sore knees and backs. And the anti-inflammatory properties from trademarked Curcumin improves delivery and absorption for fast-working relief.

Curcuminoids (active compounds in Turmeric) are linked to multiple benefits, including joint health and antioxidant protection, but are generally difficult for the body to absorb. C6’s unique CurcuWIN is, therefore significantly more effective as it is highly bioavailable and can be better absorbed by the body.

Vegan FruiteX-B is fully soluble and backed by over 10 years of research that links the compound to significant improvements in joint comfort. UC-II (patented collagen), supports joint flexibility, mobility, and health. The supplements also include green tea extract, boron, and sodium hyaluronate for a multi-faceted approach to fast, effective pain relief.

If you’re looking for a different formulation for joint health, C6 is a good place to start.

Whether you’re struggling with knee, back, wrist, or other joint pain, this is new nutritional technology for natural, effective joint medicine. Cryotherapy is a proactive approach to joint health working both to reduce inflammation and pain, as well as preventing issues related to arthritis. It is going to help improve bone strength, ligament health and deliver real results.

NutriRise Glucosamine Chondroitin MSM Turmeric

Nutririse Joint Supplement

NutriRise supplements are made in the USA and offer the highest Glucosamine concentrations. The product is all-natural, delivering an ideal pain relief solution for aching joints. It’s designed to reduce inflammation, improve cartilage strength, boost antioxidant activity, and increase joint mobility. Designed for joint pain in the back, knees, hands, and knees, its increased strength offers some of the highest levels of satisfaction among users.

NutriRise supplements are designed for optimal absorption so you can experience faster results and contain no binders, fillers, flavors, or preservatives; they’re also free from gluten, dairy, soy, and magnesium stearate. Containing Glucosamine, Chondroitin Sulfate, Turmeric powder, MSM powder, Boswellia Extract, Quercetin, Methionine, and Bromelain, the supplement combines powerful ingredients to offer the best results.

If you’re suffering from back or neck pain due to hours at a desk or knee or shoulder pain from overexertion injuries, this leading Glucosamine Chondroitin joint supplement can help. Optimal joint function is at the root of many daily activities. Still, these can become more difficult over time as the cartilage in the joints (which protects them) begins to break down, which is a trigger for inflammation that causes swelling and pain and other symptoms such as stiffness and a decreased range of motion.

The supplements are endorsed by clinical trials and use a potent combination of powerful ingredients to offer effective pain relief and reduce inflammation for men and women. The primary benefits are reduced inflammation and swelling (due to the potent concentration of MSM along with Boswellia extract and Turmeric), improved cartilage and bone strength (due to the highest concentrations of Glucosamine). Additionally, the formulation offers soothing for stiff joints (due to Methionine and Quercetin that offer natural pain relief) and improved joint lubrication and mobility (thanks to Chondroitin Sulfate, which improves water retention in the joints.)

NOW Supplements, Glucosamine & Chondroitin with MSM

Now Joint Supplement Label

NOW Glucosamine & Chondroitin with MSM supplements combine optimal levels of the three most effective and well-known compounds for supporting and promoting healthy joints. NOW’s joint supplements are based on scientific studies that have linked Glucosamine and Chondroitin to improved joint mobility and comfort supported by MSM, a naturally-occurring sulfur compound needed for healthy joint structures.

The supplements are classified as free from corn, dairy, eggs, gluten, nuts, and soy, and are Halal. Packaged in the USA according to the strictest standards, they have NPA A-rated GMP certification that covers every aspect of production, including laboratory and testing methods.

NOW Supplements have been pioneers in the natural products industry since they first started in 1968. As a family-owned and operated business, they focus on providing safe, effective natural products that empower their clients to live healthier lives. This is evidenced by their core values, which are designed around four main pillars: quality, sustainability, charitable giving, and being a family-owned and operated business.

Users rate the product highly based on its efficacy and because their products contain the potencies of the ingredients listed on the label. In particular, they note Now’s Glucosamine supplements as offering a noticeable reduction in stiffness and pain as well as a marked improvement in mobility.

Viva Naturals Glucosamine with Chondroitin Turmeric MSM Boswellia

Viva Naturals Joint Supplement

Viva Naturals offers the triple strength concentration of Glucosamine, Chondroitin, and MSM, making it the ideal supplement for joint pain, as well as for maintaining joint and cartilage health. Containing 1500 mg of Glucosamine, 200 mg Chondroitin Sulfate, and 50 mg of MSM, this formula is one of the most popular choices for men and women.

Added to the formula to improve efficacy is the clinically-studied 5-LOXIN Boswellia Serrata Extract, which offers support for healthy joints and means that you can return to normal daily activities sooner. Vitamin A (Beta-Carotene) is included in this unique formulation to assist with bone strength and joint health.

Other important compounds include Turmeric and Hyaluronic Acid. Turmeric Curcumin offers antioxidant protection and healthy joint function, while Hyaluronic Acid (Sodium Hyaluronate) helps to keep joints lubricated and allows for smooth movements, ideal for use pre and post-workout.

As with all Viva Naturals products, this joint supplement is GMP-certified and third-party tested as a guarantee that the manufacturing standards and practices are of the highest standards and have been FDA-inspected. The joint support formula is made in America following the strictest lab safety and sterilization methods. Each batch produced is third-party tested for independent verification that the product is high quality, completely pure, and matches the advertised potency. They also offer a money-back guarantee.

Frequently Asked Questions About Joint Supplements

When should I start taking a joint supplement?

As we age, our bodies become less effective at absorbing nutrients, which has important implications for the aging process. If you’re in your thirties or forties, it’s a good time to start thinking about a joint supplement, especially as most offer preventative benefits so that you don’t develop joint disorders down the line. Glucosamine occurs naturally in our bodies, but the levels decrease as we get older unless supplementing with Glucosamine (or eating a Glucosamine-rich diet). As you head toward 35, you may start noticing the occasional ache or twinge, which may mean that you need to boost your body’s natural levels of Glucosamine so that you can keep your cartilage healthy.

Why should a joint supplement include Glucosamine?

Glucosamine is an essential component of cartilage that protects your bones and keeps them from rubbing up against each other, which leads to pain and inflammation. It may also help prevent cartilage breakdown (most commonly associated with arthritis).
The two types of Glucosamine commonly found in joint supplements are Glucosamine Hydrochloride and Glucosamine Sulfate, with studies indicating that Glucosamine Sulfate may be more effective if you have osteoarthritis. It is also linked to slowing the progression of this degenerative condition if taken for longer periods.

Is Chondroitin an important ingredient in a joint supplement?

Chondroitin is also one of the core building blocks of cartilage. It has been linked to preventing the breakdown of cartilage, slowing the progression of osteoporosis (when taken long-term), and it may also reduce joint pain and stiffness.


In terms of best overall performance, we chose the Vimerson Health Glucosamine with its high-quality formulation, consistently high standards, and excellent user reviews. It’s a joint supplement that contains the most important ingredients for fighting joint pain and inflammation.

Our choice for the best price is the Arazo Nutrition Joint Support, with its range of health benefits and powerful high-quality ingredients (including Glucosamine, Chondroitin, MSM and Hyaluronic Acid, Turmeric, and Boswellia) all for a surprisingly affordable price. It also has thousands of five-star reviews that indicate a continued commitment to providing an industry-leading product.

In addition to the Vimerson Health and Arazo joint supplements, we reviewed a number of the other top products on the market. They are all excellent options if you are looking to improve your joint health and get relief from pain and discomfort.

Each product was selected and reviewed based on the reputation of the brand, the quality of the ingredients used, and feedback from thousands of other reviewers. If you’re looking for a best-in-class joint supplement, we’ve covered the most effective options so you can find the one that works best for your needs.